Alexander J Lazar Selected Research

Hemangiosarcoma (Angiosarcoma)

1/2022	Clinical activity of checkpoint inhibitors in angiosarcoma: A retrospective cohort study.
1/2021	Combined VEGFR and MAPK pathway inhibition in angiosarcoma.
1/2021	INSM1 Expression in Angiosarcoma.
1/2018	Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.
8/2017	Index report of cutaneous angiosarcomas with strong positivity for tyrosinase mimicking melanoma with further evaluation of melanocytic markers in a large angiosarcoma series.
4/2014	ERG and FLI1 protein expression in epithelioid sarcoma.
6/2013	Angiosarcoma: a tissue microarray study with diagnostic implications.
4/2013	Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer.
11/2012	Expression of ERG, an Ets family transcription factor, distinguishes cutaneous angiosarcoma from histological mimics.
9/2012	INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcoma.

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Alexander J Lazar Research Topics

Disease

134	Neoplasms (Cancer) 09/2022 - 04/2007
42	Melanoma (Melanoma, Malignant) 01/2022 - 12/2008
41	Sarcoma (Soft Tissue Sarcoma) 04/2022 - 08/2008
30	Neoplasm Metastasis (Metastasis) 01/2021 - 12/2009
17	Neurofibrosarcoma (MPNST) 01/2022 - 05/2009
14	Liposarcoma 01/2022 - 03/2011
11	Aggressive Fibromatosis (Desmoid) 01/2022 - 08/2011
11	Hemangiosarcoma (Angiosarcoma) 01/2022 - 07/2010
8	Leiomyosarcoma 05/2021 - 05/2010
7	Ewing Sarcoma (Sarcoma, Ewing) 07/2020 - 04/2009
6	Myxoid Liposarcoma 01/2022 - 01/2012
6	Synovial Sarcoma (Synovioma) 01/2020 - 04/2015
5	Carcinogenesis 01/2022 - 02/2013
4	Osteosarcoma (Osteogenic Sarcoma) 01/2022 - 01/2018
4	Disease Progression 01/2022 - 08/2016
4	Uveal melanoma 11/2020 - 01/2017
4	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 10/2015 - 03/2010
4	Solitary Fibrous Tumors 07/2015 - 11/2011
3	Colitis 01/2022 - 12/2018
3	Breast Neoplasms (Breast Cancer) 01/2020 - 04/2013
3	Testicular Neoplasms (Testicular Cancer) 05/2019 - 04/2015
3	Fibroma (Fibromatosis) 01/2019 - 12/2015
3	Neurofibroma 05/2017 - 06/2009
3	Genetic Translocation (Chromosomal Translocation) 12/2016 - 08/2011
3	Carcinoma (Carcinomatosis) 11/2015 - 04/2010
2	Desmoplastic Small Round Cell Tumor 04/2022 - 10/2018
2	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 01/2021
2	Alveolar Soft Part Sarcoma 01/2020 - 12/2009
2	Chondrosarcoma 10/2019 - 04/2015
2	Renal Cell Carcinoma (Grawitz Tumor) 09/2018 - 04/2010
2	Microsatellite Instability 01/2018 - 04/2012
2	Aneuploidy (Aneuploid) 01/2018 - 01/2018
2	Genomic Instability 03/2016 - 01/2016

Drug/Important Bio-Agent (IBA)

30	Proteins (Proteins, Gene)FDA Link 04/2022 - 12/2008
18	Immune Checkpoint InhibitorsIBA 12/2021 - 01/2016
18	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2011
13	Biological ProductsIBA 01/2022 - 09/2011
8	Messenger RNA (mRNA)IBA 10/2021 - 11/2011
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 12/2008
8	ParaffinIBA 01/2020 - 06/2009
8	DNA (Deoxyribonucleic Acid)IBA 11/2018 - 12/2009
7	Phosphotransferases (Kinase)IBA 01/2022 - 10/2013
7	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 02/2013
7	MicroRNAs (MicroRNA)IBA 01/2022 - 04/2012
7	RNA (Ribonucleic Acid)IBA 01/2021 - 04/2015
6	Transcription Factors (Transcription Factor)IBA 01/2021 - 12/2009
6	CateninsIBA 10/2018 - 08/2011
6	Formaldehyde (Formol)FDA Link 01/2018 - 06/2012
5	pembrolizumabIBA 01/2022 - 10/2016
5	ChromatinIBA 01/2022 - 01/2016
5	Imatinib Mesylate (Gleevec)FDA Link 01/2022 - 08/2009
5	Keratins (Keratin)IBA 10/2021 - 04/2007
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2020 - 08/2009
5	AntigensIBA 05/2019 - 01/2011
5	IpilimumabIBA 11/2018 - 10/2016
4	LigandsIBA 01/2022 - 06/2011
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 05/2010
4	Pharmaceutical PreparationsIBA 01/2021 - 04/2010
4	Histones (Histone)IBA 01/2021 - 08/2015
4	SurvivinIBA 08/2017 - 12/2011
4	Indicators and Reagents (Reagents)IBA 05/2017 - 01/2016
4	Cyclin D1IBA 01/2016 - 05/2009
3	Telomerase (Telomerase Reverse Transcriptase)IBA 03/2022 - 06/2013
3	Sorafenib (BAY 43-9006)FDA Link 01/2022 - 12/2008
3	Oncogene Proteins (Oncogene Protein)IBA 01/2022 - 12/2016
3	trametinibIBA 01/2021 - 08/2016
3	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 01/2021 - 11/2014
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2020 - 08/2012
3	NucleotidesIBA 01/2018 - 06/2015
3	TOR Serine-Threonine KinasesIBA 12/2016 - 05/2009
3	Small Interfering RNA (siRNA)IBA 11/2015 - 06/2011
2	S100 Proteins (S 100 Protein)IBA 09/2022 - 01/2017
2	SAR405838IBA 01/2022 - 03/2016
2	Long Noncoding RNAIBA 01/2022 - 10/2020
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 09/2012
2	EnzymesIBA 05/2021 - 01/2021
2	Glucose (Dextrose)FDA LinkGeneric 05/2021 - 01/2021
2	Transaminases (Aminotransferases)IBA 05/2021 - 02/2012
2	Serine (L-Serine)FDA Link 01/2021 - 10/2013
2	dabrafenibIBA 01/2021 - 08/2016
2	Lysine (L-Lysine)FDA Link 01/2021 - 01/2021
2	Mitogen-Activated Protein KinasesIBA 01/2021 - 01/2020
2	CytokinesIBA 11/2020 - 02/2016
2	AntibodiesIBA 07/2020 - 04/2014
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2020 - 01/2018
2	Tyrosine Kinase InhibitorsIBA 01/2019 - 06/2011
2	NivolumabIBA 11/2018 - 09/2018
2	Circulating Tumor DNAIBA 10/2018 - 01/2018
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2018 - 01/2016
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2018 - 02/2013
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2017 - 06/2011

Therapy/Procedure

62	Therapeutics 01/2022 - 05/2009
19	Immunotherapy 01/2022 - 07/2012
13	Drug Therapy (Chemotherapy) 01/2022 - 04/2009
12	Radiotherapy 01/2020 - 12/2011
5	Precision Medicine 12/2017 - 01/2016
4	Neoadjuvant Therapy 10/2018 - 03/2010
3	Combined Modality Therapy 01/2020 - 01/2019
2	Investigational Therapies (Experimental Therapy) 01/2020 - 04/2009
2	Fecal Microbiota Transplantation 01/2019 - 12/2018